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How does buprenorphine work in the brain? How does Buprenorphine work in the brain ? Opioids attach to receptors in the brain, with three main effects; reduced respiration, euphoria, decreased pain. It too binds to the receptors, however, without a perfect fit. As a result the Buprenorphine tends to occupy the receptors without all of the opioid effects.
Is Naloxone a mat? Naloxone. Naloxone is a medication used in medication-assisted treatment (MAT) to counter opioid overdose.
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