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I have been receiving Zometa via IV infusion for about 3 years now - At first three weekly then after about a year, four weekly - I have breast cancer, bone metastasis. If I take the infusion over 15 minutes....during the following day I will begin with severe vomiting and flu symptoms which last for two days and nights after which I'm fine. However, if I have the infusion over 30 minutes - as advised on the internet way back in the early days of my treatments, I have NO side effects whatsoever - no sickness, no aches & pains! I have spoken to other women who have experienced the same - take the infusion slower, drink plenty of water, and you might just find your horrid side-effects disappear!

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